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3 . 2018
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Molecular typing of the Vibrio parahaemoiyticus strains by INDEL markers

Abstract

A method of genotyping Vibrio parahaemolyticus strains based on the definition of "deletions-inserts" (INDEL-markers) was developed. The typing of V. parahaemolyticus strains isolated from sea water, from hydrobionts and people in the regions of the Black, Azov, Caspian and Japanese Seas was carried out by 6 INDEL-loci from 1972 to 2015. INDEL-typing method allowed to identify 25 genotypes, which were distributed between 5 clusters. The correlation of distribution of V. parahaemolyticus strains on clusters depending on the presence of genes of the main factors of pathogenicity and belonging to the "pandemic" clone was revealed.

Keywords:Vibrio parahaemolyticus, INDEL-typing, vibrios, genotype, thermostable direct hemolysin TDH, TDHrelated hemolysin TRH

Infectious Diseases: News, Opinions, Training. 2018; 7 (3): 26-30. doi: 10.24411/2305-3496-2018-13004

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CHIEF EDITOR
CHIEF EDITOR
Aleksandr V. Gorelov
Academician of the Russian Academy of Sciences, MD, Head of Infection Diseases and Epidemiology Department of the Scientific and Educational Institute of Clinical Medicine named after N.A. Semashko ofRussian University of Medicine, Ministry of Health of the Russian Federation, Professor of the Department of Childhood Diseases, Clinical Institute of Children's Health named after N.F. Filatov, Sechenov First Moscow State Medical University, Ministry of Health of the Russian Federation, Deputy Director for Research, Central Research Institute of Epidemiology, Rospotrebnadzor (Moscow, Russian Federation)
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